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Ezmin 250mg Tab

EZMIN (Azithromycin) is an azolid, a subclass of macrolide antibiotics, active against Gram-positive and Gram-negative organisms for oral administraion. Azithromycin is rapidly absorbed and widely distributed throughout the body.

EZMIN (Azithromycin) acts by binding to the 50S ribosomal subunit of susceptible organisms and thus interfering with microbial protein synthesis.

Description Wt/Vol
Ezmin 250mg Tab
Each Film Coated Tablet Contains:
Azithromycin (as Dihydrate) B.P. 250 mg
EZMIN (Azithromycin) is indicated in upper respiratory tract infections, including pharyngitis, tonsillitis, sinusitis, otitis media, lower respiratory tract infections including acute bronchitis, acute exacerbation of chronic obstructive lung disease, bacterial and a typical pneumonia, skin and soft tissue infections. In sexually transmitted disease in men and women EZMIN is indicated in the treatment of uncompleted genital infections due to chlamydia trachomatis.
Adult: Lower respiratory tract infections including bronchitis, pneumonia, upper respiratory tract infections, including sinusitis, pharyngitis, tonsillitis, otitis media, skin and soft tissue infections. 2 tablets once daily for 3 days. An alternative to this dosage schedules is 2 tablets once for first day followed by 1 tablet once daily for next 4 days.

Sexually transmitted disease caused by Chlamydia trachomatis. 4 tablet given as a single dose.
Azithromycin absorption is reduced by 50% in presence of food in the stomach. It should therefore be taken 1 hour before or 2 hours after meal. Macrolides have been known to increase the plasma concentration of digoxia and cyclosporine. Therefore, if co-administration is necessary caution should be exercised and serum should be taken in patients with hepatic and severe renal impairment. No adverse effects on fetus during pregnancy are reported. However, caution should be exercised as with other drugs.
Azithromycin is well tolerated with a low incidence of side effects. Majority of the side effects are mild to moderate in nature and of gastrointestinal in origin with nausea, abdominal discomfort, vomiting, flatulence, diarrhea and loose motion. Allergic reactions, such as rash have occurred in case of hypersensitive patients.
EZMIN is contraindicated in patients with known hypersensitivity to Azithromycin and with hepatic disease.